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CORRESPONDENCE: Imiquimod for Vulvar Intraepithelial Neoplasia
Mercredi 02 Juillet 2008 - 06:55 - 5 mois depuis - Presse spécialisée - New England Journal of Medicin
To the Editor: Van Seters et al. (April 3 issue)1 report that regression of vulvar intraepithelial neoplasia was significantly greater ...

CORRESPONDENCE: Correction: Drug-Review Deadlines and Safety Problems
Mercredi 02 Juillet 2008 - 06:55 - 5 mois depuis - Presse spécialisée - New England Journal of Medicin
To the Editor: Carpenter et al. (March 27 issue)1 report that new molecular entities (NMEs) approved in the 2 months ...

EARLY RELEASE: Noninvasive Monitoring of Tumors
Mercredi 02 Juillet 2008 - 06:55 - 5 mois depuis - Presse spécialisée - New England Journal of Medicin
(No abstract is available for this citation)

Le VIH/SIDA, une catastrophe ? - Afrik.com
Mercredi 02 Juillet 2008 - 06:54 - 5 mois depuis - Presse généraliste - Google santé france
En négligeant les besoins des personnes touchées par le VIH dans ces situations, les organisations humanitaires risquent toutefois de causer encore plus de dégâts, selon l’édition 2008 du Rapport sur les catastrophes dans le monde, publiée le 26 juin ...

Could Our Own Proteins Be Used to Help Us Fight Cancer? [Scientific American Magazine]
Mercredi 02 Juillet 2008 - 06:33 - 5 mois depuis - Presse spécialisée - Scientific American
In 1962 someone at the Genetics Institute in Pavia, Italy, turned up the temperature in an incubator holding fruit flies. When Ferruccio Ritossa, then a young geneticist, examined the cells of these “heat shocked” flies, he noticed that their chromosomes had puffed up at discrete locations. The puffy appearance was a known sign that genes were being activated in those regions to give rise to their encoded proteins, so those sites of activity became known as the heat shock loci.The effect was reproducible but initially considered to be unique to the fruit fly. It took another 15 years before the proteins generated when these chromosome puffs appear were detected in mammals and other forms of life. In what is certainly among the most absorbing stories in contemporary biology, heat shock proteins (HSPs) have since been recognized as occupying a central role in all life--not just at the level of cells but of organisms and whole populations. [More]

Could Our Own Proteins Be Used to Help Us Fight Cancer?
Mercredi 02 Juillet 2008 - 06:33 - 5 mois depuis - Cancer - Scientific American
In 1962 someone at the Genetics Institute in Pavia, Italy, turned up the temperature in an incubator holding fruit flies. When Ferruccio Ritossa, then a young geneticist, examined the cells of these “heat shocked” flies, he noticed that their chromosomes had puffed up at discrete locations. The puffy appearance was a known sign that genes were being activated in those regions to give rise to their encoded proteins, so those sites of activity became known as the heat shock loci.The effect was reproducible but initially considered to be unique to the fruit fly. It took another 15 years before the proteins generated when these chromosome puffs appear were detected in mammals and other forms of life. In what is certainly among the most absorbing stories in contemporary biology, heat shock proteins (HSPs) have since been recognized as occupying a central role in all life--not just at the level of cells but of organisms and whole populations. [More]

Looking at Yesterday's Genes for Tomorrow's Cures [Scientific American Magazine]
Mercredi 02 Juillet 2008 - 06:31 - 5 mois depuis - Presse spécialisée - Scientific American
If humans could reanimate one of our ancient ancestors, we could quickly learn much more about how people once went about their lives than any study of dusty bones and artifacts would reveal. Our forebear might even teach us a few old tricks that could be used to help the living.That is in essence what researchers in Germany and Hungary were after when they re-created Harbinger3_DR, a long-extinct precursor of at least two modern human genes: they wanted to watch it operate inside living cells. Not just any DNA relic, Harbinger3_DR is an ancient transposon--a so-called jumping gene, able to cut itself out of an organism’s genome and reinsert itself in a different location. Modern scientists would love to master its secrets so they could more precisely control where genes introduced for gene therapy incorporate themselves into a patient’s DNA strand. [More]

La fin des publicités alimentaires pour les enfants ? - Doctissimo
Mercredi 02 Juillet 2008 - 06:13 - 5 mois depuis - Presse généraliste - Google santé france
Face au fléau d'obésité infantile annoncé, plus de vingt associations et sociétés savantes soutiennent le projet de Roselyne Bachelot, ministre de la santé, de limiter la publicité télévisuelle alimentaire destinée aux enfants. ...

Le festival Solidays fête ses 10 ans - Doctissimo
Mercredi 02 Juillet 2008 - 06:13 - 5 mois depuis - Presse généraliste - Google santé france
Pour la 10e année consécutive, le festival Solidays prend ses marques à l'hippodrome de Longchamp. Pendant trois jours, les 4, 5 et 6 juillet prochains, 80 concerts s'enchaînent à un rythme endiablé pour une cause : lutter contre le sida. ...

KRAS Mutations Predictive But Not Prognostic in Colorectal Cancer
Mercredi 02 Juillet 2008 - 05:27 - 5 mois depuis - Presse spécialisée - Medscape family medicine
Another study has confirmed that KRAS mutations predict response to cetuximab in colorectal cancer, but shows that they are not prognostic. Medscape Medical News

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